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KMID : 0388019920030010024
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Korean Journal Gynecologic Oncology and Colposcopy
1992 Volume.3 No. 1 p.24 ~ p.29
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Preoperative Serum CA-125 Level in Endometrial Carcinoma: Correlate with Prognostic Variables
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김낙연
안치석/김병기/송용상/김우호/강순범/이효표
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Abstract
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We evaluated 21 women with endometrial carcinoma to determine the relationship between the preoperative tumor marker CA-125 level and the postoperative histologic grade and depth of myometrial invasion, from February 1987 to February 1991, In all
patients, the clinical stage was I roⅡ.
In hsitologic grade, serum CA-125 level was elevated(>35 U/ml)in 25.0%(2/8) of patients with G1, 20.0%(2/10) of patients with G3. There was not a significant relationship between elevated serum CA-125 level and histologic garde. In depth of
myhometrial
invasion, serum CA-125 level was elevated(>35 U/ml) in 6.7%(1/15) of patients with less than half of the myometrium and 66.7%(4/6) of patients with more than half of the myometrium. A statistically significant relationship was recorded when the
tumor
had penetrated more than hafl of the myometrium.
Preoperative evaluation of serum CA-125 level could be successfully combined with other techniques in therapy planning of endomeral carcinoma.
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KEYWORD
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